Location History:
- Los Altos, CA (US) (2002 - 2016)
- South San Francisco, CA (US) (2021)
Company Filing History:
1 out of 12 
1 out of 257 
1 out of 1 Years Active: 2002-2021
Title: The Innovations of David Morgans: A Pioneer in Molecular Biology
Introduction
David Morgans, a distinguished inventor based in Los Altos, CA, has made significant contributions to the field of molecular biology through his innovative inventions. With two patents to his name, Morgans is recognized for his work on E3 ubiquitin ligases and hydrolytic enzyme substrates.
Latest Patents
One of Morgans’ notable patents is titled "Method for Identifying Modulators of Ubiquitin Ligases." This invention provides a screening method that exploits mechanism-based activity probes, specifically designed to covalently modify the active site cysteine thiol residue of E3 ubiquitin ligases, notably including the HECT and RBR families. These activity probes allow for the screening of activators and inhibitors of E3 ubiquitin ligases, enabling researchers to assess their functional states in the context of human diseases.
His second patent, "Hydrolytic Enzyme Substrates and Assay Method," introduces compounds with the structure D–L–A*, where L serves as a linking moiety optimizing the configuration of D and A for Förster Resonance Energy Transfer (FRET). This innovation is particularly useful as a fluorescent substrate for detecting enzymes in vivo, contributing to advancements in biochemical assays.
Career Highlights
Throughout his career, David Morgans has collaborated with notable companies in the biotechnology sector, including Iconix Pharmaceuticals, Inc. and E3x Bio, Inc. His work at these organizations has enhanced the understanding and application of his patented technologies.
Collaborations
Morgans has had the opportunity to work alongside talented individuals in his field, including coworkers Kurt Jarnigan and Roger Leger. These collaborations have undoubtedly benefited his research and development efforts, contributing to the success of his innovations.
Conclusion
David Morgans exemplifies the innovative spirit that drives advancements in molecular biology. His patented inventions not only showcase his creativity and expertise as an inventor but also hold significant potential for research applications in understanding and treating human diseases. As he continues to collaborate with industry professionals, the impact of his work is likely to grow even further, inspiring future innovations in the field.