Company Filing History:
Years Active: 2002-2008
Title: David Hoover: Innovator in Vaccine Development
Introduction
David Hoover is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of vaccine development, particularly in the area of live attenuated vaccines. With a total of 2 patents, Hoover's work has the potential to impact public health positively.
Latest Patents
Hoover's latest patents focus on live attenuated vaccines against brucellosis and other diseases. One of his key discoveries involves the trans complementation of the wboA gene, which can be utilized to maintain an expression vector in an attenuated host cell within a vaccinee. This innovative approach allows for the expression of heterologous antigens, enabling the creation of a multivalent vaccine targeting various diseases. Additionally, he has developed methods for preparing live Brucella vaccines that are protective against brucellosis. These vaccines are created by introducing a deletion in the rfbU gene of a Brucella strain, resulting in attenuation while preserving the necessary immunogenicity to elicit a protective immune response.
Career Highlights
David Hoover is currently employed by the US Government as represented by the Secretary of the Army. His work in vaccine research and development has garnered attention for its potential to address significant health challenges.
Collaborations
Hoover has collaborated with notable colleagues, including Mikeljon Nikolich and Richard Lloyd Warren. Their combined expertise contributes to the advancement of innovative solutions in vaccine technology.
Conclusion
David Hoover's contributions to vaccine development, particularly in the area of live attenuated vaccines, highlight his role as an influential inventor. His work not only showcases his innovative spirit but also emphasizes the importance of collaboration in advancing public health initiatives.