The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2002

Filed:

Jan. 22, 1998
Applicant:
Inventors:

Mikeljon P. Nikolich, Takoma Park, MD (US);

David L. Hoover, Rockville, MD (US);

Richard L. Warren, Blue Bell, PA (US);

Luther E. Lindler, Wheaton, MD (US);

Ted L. Hadfield, Colesville, MD (US);

Gerhardt G. Schurig, Blacksburg, VA (US);

Stephen M. Boyle, Blacksburg, VA (US);

John R. McOulston, Blacksburg, VA (US);

Nammalwar Sriranganathan, Blacksburg, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/106 ;
U.S. Cl.
CPC ...
C12P 2/106 ;
Abstract

Live Brucella vaccines and methods for preparing the live vaccines protective against brucellosis are described. The vaccines are prepared by introducing a deletion in the rfbU gene of a strain of Brucella which results in attenuation of the strain while retaining the desired immunogenicity to initiate a protective immunogenic response. Other strains with varying levels of attenuation are described.


Find Patent Forward Citations

Loading…