Company Filing History:
Years Active: 2002-2008
Title: Mikeljon Nikolich: Innovator in Vaccine Development
Introduction
Mikeljon Nikolich is a prominent inventor based in Takoma Park, MD (US). He has made significant contributions to the field of vaccine development, particularly in the area of live attenuated vaccines. With a total of 2 patents, his work has the potential to impact public health positively.
Latest Patents
Nikolich's latest patents focus on live attenuated vaccines against brucellosis and other infectious diseases. One of his notable inventions describes the use of trans complementation of the wboA gene to maintain an expression vector in an attenuated host cell within a vaccinee. This innovative approach allows for the expression of heterologous antigens, enabling the creation of a multivalent vaccine targeting various diseases. Additionally, he has developed methods for preparing live Brucella vaccines that are protective against brucellosis. These vaccines are created by introducing a deletion in the rfbU gene of a Brucella strain, resulting in attenuation while preserving the necessary immunogenicity to elicit a protective immune response.
Career Highlights
Mikeljon Nikolich is currently associated with the US Government as represented by the Secretary of the Army. His work in vaccine research and development has garnered attention for its potential applications in combating infectious diseases.
Collaborations
Nikolich has collaborated with notable colleagues, including David Hoover and Richard Lloyd Warren, contributing to advancements in vaccine technology.
Conclusion
Mikeljon Nikolich's innovative work in vaccine development showcases his commitment to improving public health through scientific research. His patents reflect a dedication to creating effective solutions for infectious diseases, making him a significant figure in the field of immunology.