David Buckley

Title: David Buckley: Innovator in Separation and Chromatography Technologies

Introduction

David Buckley is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of separation technologies, particularly through his innovative methods for preparing separation matrices and chromatography matrices. With a total of 2 patents, Buckley's work has implications for various applications, including protein purification.

Latest Patents

David Buckley's latest patents include a method of preparing a separation matrix and a method of preparing a chromatography matrix. The first patent relates to a method for creating an insoluble separation matrix through salt-treatment of a polysaccharide gel followed by cross-linking. This method involves providing an aqueous solution of a gelatable native polysaccharide, lowering the temperature below its gelling point, adding at least one salt, and cross-linking the resulting polysaccharide. The polysaccharide can be formed into particles, membranes, or monoliths.

The second patent focuses on a method for preparing a porous cross-linked polysaccharide chromatography matrix. This process includes providing an aqueous solution of a gellable polysaccharide, substituting part of the hydroxyl groups with non-nucleophilic groups, forming spherical droplets, gel formation, and cross-linking the gel with a cross-linking agent. This invention also encompasses a chromatography column packed with the produced matrix, which can be utilized in protein purification.

Career Highlights

Throughout his career, David Buckley has worked with prominent companies such as GE Healthcare Bio-Sciences AB and GE Healthcare Bioprocess R&D AB. His experience in these organizations has allowed him to develop and refine his innovative techniques in separation and chromatography technologies.

Collaborations

David has collaborated with notable professionals in his field, including Hans Berg and Anders Hagvall. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

David Buckley is a distinguished inventor whose work in separation and chromatography technologies has led to significant advancements in the field. His innovative methods and collaborations continue to influence the industry and pave the way for future developments.