David B Go

Title: Innovator Spotlight: David B. Go – Pioneering Advances in Microfluidics

Introduction

David B. Go, an accomplished inventor based in South Bend, Indiana, holds five patents that showcase his pioneering work in the field of microfluidics and biotechnology. His innovative spirit and dedication to advancing medical technologies have made significant contributions to both research institutions and industry.

Latest Patents

David's latest patents include groundbreaking technologies that enhance processes in polymerase chain reactions and exosome isolation. One of his notable inventions, titled "AC electrosprayed droplets for digital and emulsion PCR," introduces an alternating current electrospray technology capable of generating micron-sized droplets in oil at exceptionally high throughput for emulsion or digital PCR. This technology dramatically surpasses the traditional flow-focusing methods, achieving up to a hundred times greater throughput. With the ability to generate up to a trillion monodispersed droplets in about one hour, it offers a transformative solution in PCR methodologies.

Another significant invention, "Simultaneous isolation and preconcentration of exosomes by ion concentration polarization method and apparatus," addresses the existing challenges in exosome extraction. This invention employs a novel microfluidic technique that allows for the efficient isolation of exosomes, which are crucial for cancer biomarker analysis. Utilizing an ion-selective membrane in conjunction with pressure-driven flow, this innovation captures between 60% to 80% of exosomes from various biofluids, significantly improving recovery rates when compared to traditional techniques.

Career Highlights

David has collaborated with esteemed institutions, including the University of Notre Dame Du Lac, where he has contributed to vital research initiatives. Additionally, his tenure at Intel Corporation reflects his versatility and ability to bridge the gap between academic research and practical application in technology development.

Collaborations

Throughout his career, David has worked alongside notable colleagues, including Hsueh-Chia Chang and Rajiv K. Mongia, who have also made significant contributions to the fields of microfluidics and biotechnology. These collaborations have fostered an environment where innovative ideas can flourish and lead to practical solutions that address pressing challenges in medical technology.

Conclusion

David B. Go stands as a remarkable figure in the realm of innovation, with his patents embodying the potential to transform how we approach critical biological processes. His work not only enhances scientific research but also opens new pathways for diagnostics and therapeutics in the medical field. As he continues to explore the frontiers of technology, his contributions will undoubtedly leave a lasting impact on the landscape of biomedicine and beyond.