David A Kass

Title: David A Kass: Innovator in Engineered Polypeptides and Heart Function Improvement

Introduction

David A Kass is a prominent inventor based in Columbia, MD (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of engineered polypeptides and methods for improving heart function. With a total of 11 patents to his name, Kass continues to push the boundaries of innovation in healthcare.

Latest Patents

One of Kass's latest patents involves engineered TSC2 polypeptides. This invention provides engineered TSC2 polypeptides and nucleic acid sequences encoding them, where the ability of a serine residue to be phosphorylated is altered. In certain aspects, the TSC2 serine residue cannot be phosphorylated, such as by substituting the serine residue with an alanine residue. In other aspects, the TSC2 serine acts as if it is constitutively phosphorylated, for example, by substituting the serine residue with a glutamic acid residue. Additionally, this patent includes engineered immune cells comprising altered TSC2 polypeptides or nucleic acid sequences encoding them, along with methods for making and using such engineered immune cells. Another significant patent focuses on methods for improving heart function, providing innovative approaches to enhance cardiac health.

Career Highlights

Throughout his career, David A Kass has worked with esteemed institutions such as Johns Hopkins University and the National Institutes of Health, a component of the US Department of Health & Human Services. His work in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Kass has collaborated with notable colleagues, including David A Wink and Martin Feelisch. These partnerships have further enriched his research and innovation efforts.

Conclusion

David A Kass stands out as a key figure in the realm of biomedical innovation. His contributions through patents and collaborations have the potential to significantly impact healthcare and improve patient outcomes.