The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Dec. 30, 2008
David A. Wink, Hagerstown, MD (US);
Martin Feelisch, Shreveport, LA (US);
Pasquale Pagliaro, Turin, IT;
David A. Kass, Columbia, MD (US);
Nazareno Paolocci, Baltimore, MD (US);
Katrina M. Miranda, Tucson, AZ (US);
Jon M. Fukuto, Agoura, CA (US);
David A. Wink, Hagerstown, MD (US);
Martin Feelisch, Shreveport, LA (US);
Pasquale Pagliaro, Turin, IT;
David A. Kass, Columbia, MD (US);
Nazareno Paolocci, Baltimore, MD (US);
Katrina M. Miranda, Tucson, AZ (US);
Jon M. Fukuto, Agoura, CA (US);
Johns Hopkins University, Baltimore, MD (US);
The United States of America as represented by the Secretary of Health and Human Services, Washington, WA (US);
The Regents of the University of California, Los Angeles, CA (US);
Abstract
Nitroxyl donating compounds are administered prior to the onset of ischemia for the prevention and/or reduction of ischemia/reperfusion injury in subjects at risk for ischemia. Nitroxyl donors also are administered to organs to be transplanted for the prevention and/or reduction of ischemia/reperfusion injury upon reperfusion in a recipient. Nitroxyl donors include any nitroxyl donating compound. In particular cases the nitroxyl donor is a nitroxyl-donating diazeniumdiolate, such as Angeli's salt or IPA/NO.