Company Filing History:
Years Active: 2016-2024
Title: The Innovative Contributions of Daniele Zink
Introduction
Daniele Zink is a prominent inventor based in Singapore, known for his significant contributions to the field of biotechnology. With a total of seven patents to his name, Zink has made remarkable advancements in the development of innovative solutions for medical applications.
Latest Patents
One of Zink's latest patents is the "Thermoresponsive microcarrier system and uses thereof." This invention involves a polymeric microsphere that comprises a thermally responsive monomer crosslinked with a functional group monomer. The functional group monomer includes at least one of a carboxylic acid functional group or an amine functional group. The thermally responsive monomer is preferably N-isopropylacrylamide (NIPAM), and the microspheres are designed to have a coating of polymerized catecholamines, such as DOPA. This invention also outlines a method for preparing the polymeric microsphere and its applications in culturing, harvesting, or expanding stem cells or stromal cells, particularly in serum-free and xeno-free mediums.
Another notable patent is the "High throughput method for accurate prediction of compound-induced liver injury." This method and system aim to predict liver injury in vivo due to hepatocyte damage caused by a test compound. The process includes acquiring images of fluorescently stained cells from a cell culture treated with a range of doses of the test compound. The method involves segmenting the acquired images and extracting various phenotypic features for analysis. By normalizing results from treated samples to vehicle controls, the method predicts the probability of liver injury based on changes in the extracted features using machine learning techniques.
Career Highlights
Daniele Zink is currently affiliated with the Agency for Science, Technology and Research, where he continues to push the boundaries of innovation in biotechnology. His work has garnered attention for its potential impact on medical research and applications.
Collaborations
Zink has collaborated with notable figures in the field, including Jackie Yi-Ru Ying and Ming Ni. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Daniele Zink's innovative work in biotechnology, particularly through his recent patents, showcases his commitment to advancing medical science. His contributions have the potential to significantly impact the fields of stem cell research and liver injury prediction.