Altadena, CA, United States of America

Daniela Castanotto

USPTO Granted Patents = 6 

Average Co-Inventor Count = 2.6

ph-index = 1


Location History:

  • Altadena, CA (US) (2013 - 2023)
  • Pasadena, CA (US) (2023)

Company Filing History:


Years Active: 2013-2023

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6 patents (USPTO):

Title: Daniela Castanotto: Innovator in Gene Delivery and Cancer Treatment

Introduction

Daniela Castanotto is a prominent inventor based in Altadena, CA (US). She has made significant contributions to the field of gene delivery and cancer treatment, holding a total of 6 patents. Her innovative work focuses on enhancing the delivery of therapeutic nucleic acids and kinase inhibitors to cancer cells.

Latest Patents

Among her latest patents, one notable invention is related to TKI permeability enhancers. This patent provides methods for delivering nucleic acids and kinase inhibitors to a cell, which are particularly useful for treating cancer. The methods involve contacting cancer cells with both a kinase inhibitor and a therapeutic nucleic acid, thereby facilitating effective treatment options. Another significant patent involves methods for intracellular delivery and enhanced gene targeting. This invention discloses methods and compositions that enhance gene targeting by co-administering a targeting molecule along with a means to enhance its function upon delivery to the cell. The enhancements may include stressors that induce cellular stress, proton sponge molecules, and endosome or lysosome inhibitors.

Career Highlights

Daniela Castanotto is affiliated with City of Hope, a leading research and treatment center. Her work at this institution has allowed her to focus on groundbreaking research that aims to improve cancer therapies through innovative gene delivery techniques.

Collaborations

Throughout her career, Daniela has collaborated with esteemed colleagues, including John J Rossi and Cy Aaron Stein. These collaborations have further enriched her research and contributed to the advancement of her inventions.

Conclusion

Daniela Castanotto's contributions to the field of gene delivery and cancer treatment are noteworthy. Her innovative patents and collaborations reflect her commitment to advancing medical science and improving patient outcomes.

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