The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2023

Filed:

Nov. 17, 2015
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Cy Aaron Stein, Pasadena, CA (US);

Daniela Castanotto, Pasadena, CA (US);

David Horne, Altadena, CA (US);

Assignee:

City of Hope, Duarte, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/10 (2006.01); A61K 31/352 (2006.01); A61K 31/404 (2006.01); A61K 31/4155 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/52 (2006.01); A61K 31/55 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 31/713 (2006.01); C12N 15/11 (2006.01); C12N 15/85 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); C12N 15/87 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 31/10 (2013.01); A61K 31/352 (2013.01); A61K 31/404 (2013.01); A61K 31/4155 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/52 (2013.01); A61K 31/55 (2013.01); A61K 31/711 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 38/005 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 15/111 (2013.01); C12N 15/85 (2013.01); C12N 15/87 (2013.01); C12N 2320/32 (2013.01);
Abstract

Provided herein are, inter alia, methods useful for delivering nucleic acids and kinase inhibitors to a cell. The methods provided herein include the delivery of therapeutic nucleic acids to cancer cells by contacting a cancer cell with a kinase inhibitor and a therapeutic nucleic acid. The methods provided herein are therefore, inter alia, useful for the treatment of cancer.


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