Company Filing History:
3 out of 5 
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1 out of 4,455 
Years Active: 2007-2021
Title: Inventor Spotlight: Daniel R. Lasko
Introduction
Daniel R. Lasko is an innovative inventor based in Medford, MA, USA. With a strong background in biotechnology, he holds a total of five patents, focusing on advanced methodologies for producing polysaccharides and glycoproteins. His work significantly contributes to the field of cell culture and fermentation processes.
Latest Patents
Among his latest patents is a remarkable invention related to media and fermentation methods for producing polysaccharides in bacterial cell culture. This invention outlines a complex culture medium that includes a vegetable hydrolysate, yeast extract, and a carbon source. Additionally, it details a defined media with a total amino acid concentration exceeding 50 mM, utilizing fed batch and perfusion fermentation methods for optimal cultivation of polysaccharide-producing bacteria.
Another critical patent by Lasko is the development of an improved system for large-scale production of glycoproteins in cell culture. This system allows cells expressing glycoproteins to be nurtured in media containing manganese at concentrations ranging from 10 to 600 nM. This innovation enhances the glycosylation pattern of the produced glycoproteins, making them more representative of their naturally occurring counterparts, which is advantageous for pharmaceutical applications.
Career Highlights
Daniel R. Lasko has an extensive career, having worked with renowned institutions such as Wyeth Research Ireland Limited and Wyeth. His contributions in these companies have been pivotal in advancing research related to cellular processes and biopharmaceutical production.
Collaborations
Throughout his career, Lasko has collaborated with esteemed coworkers, including Denis Drapeau and Yen-Tung Luan. These partnerships have fostered significant advancements in the field of biotechnology, showcasing the importance of collaborative research in achieving groundbreaking innovations.
Conclusion
In summary, Daniel R. Lasko's innovative contributions to biotechnology, particularly in the production of polysaccharides and glycoproteins, highlight his role as a prominent inventor. His patents represent substantial advancements in fermentation methods and cell culture, underscoring his commitment to innovation in the biotechnology sector.