Cyril Redcrow

Title: Innovations by Cyril Redcrow in Electrophysiological Assays

Introduction

Cyril Redcrow is a prominent inventor located in San Diego, CA, known for his significant contributions to the field of electrophysiology. With a total of four patents to his name, Redcrow's work focuses on the innovative profiling and screening of human epithelial sodium channels (hENaC), which plays a crucial role in various physiological processes.

Latest Patents

Cyril Redcrow's latest patents include groundbreaking advancements in electrophysiological assays using oocytes that express human ENaC. One such patent focuses on the use of phenamil to enhance the effects of ENaC enhancers in assays employing membrane potential reporting dyes. The invention outlines a mammalian cell-based high-throughput assay for profiling hENaC, cloned from a human kidney c-DNA library, as well as other tissues, including human taste tissue. Moreover, the patents detail amphibian oocyte-based medium-throughput electrophysiological assays aimed at identifying human ENaC modulators, with an emphasis on ENaC enhancers. These assays have distinct advantages over existing cellular expression systems, making them a robust method to detect compounds that influence salty taste in humans.

Career Highlights

Cyril Redcrow is currently associated with Senomyx, Inc., where he applies his expertise in ion channel research. His patents and research significantly contribute to understanding how compounds can modulate ENaC function, potentially leading to advances in taste-related applications.

Collaborations

Throughout his career, Cyril has collaborated with several notable professionals, including Guy Servant and Hong Chang. These partnerships enhance the breadth of research and innovation in the field, facilitating the development of new technologies and methodologies.

Conclusion

Cyril Redcrow's work reflects a deep commitment to advancing the field of electrophysiological assays. His innovative approach to understanding human ENaC and its modulators has significant implications for taste perception and therapeutic applications. As Redcrow continues to explore new frontiers, his contributions are likely to leave a lasting impact in both academic and commercial research sectors.