Belmont, MA, United States of America

Cuihua Liu

USPTO Granted Patents = 9 

 

Average Co-Inventor Count = 5.4

ph-index = 4

Forward Citations = 57(Granted Patents)


Company Filing History:


Years Active: 2012-2018

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9 patents (USPTO):Explore Patents

Title: The Innovations of Cuihua Liu

Introduction

Cuihua Liu is a prominent inventor based in Belmont, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of therapeutic proteins. With a total of 9 patents to his name, Liu's work has had a substantial impact on medical research and treatment options.

Latest Patents

Among his latest patents is a method for producing recombinant therapeutic fusion proteins derived from Chinese hamster ovary (CHO) cells. This innovative approach involves culturing CHO cells under specific conditions to express a recombinant therapeutic fusion protein that includes one or more glycans. Notably, these CHO cells are not genetically engineered to produce terminal alpha-galactosyl residues on glycans. The method also includes treating the glycans with exoglycosidases and measuring the presence of terminal galactose-alpha-1-3-galactose residues using nuclear magnetic resonance (NMR). Another significant patent focuses on methods for enriching, identifying, and quantifying unusually modified glycans, such as phosphorylated and sulfated glycans. This involves preparing glycan samples from which sialic acids have been released and employing separation techniques based on charge-to-mass ratios.

Career Highlights

Cuihua Liu is currently employed at Momenta Pharmaceuticals, Inc., where he continues to advance his research in glycoprotein products. His work is crucial in the development of therapies that can improve patient outcomes in various medical conditions.

Collaborations

Liu collaborates with notable colleagues, including Xiao-Jin Xu and Shiming Dong, who contribute to his research efforts and innovations in the field.

Conclusion

Cuihua Liu's contributions to biotechnology and his innovative patents demonstrate his commitment to advancing medical science. His work continues to pave the way for new therapeutic options and improved healthcare solutions.

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