The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Dec. 18, 2009
Cuihua Liu, Belmont, MA (US);
Xiao-jin Xu, Jamaica Plain, MA (US);
Shiming Dong, North Reading, MA (US);
Guy Dellorusso, Milford, MA (US);
Cuihua Liu, Belmont, MA (US);
Xiao-Jin Xu, Jamaica Plain, MA (US);
Shiming Dong, North Reading, MA (US);
Guy Dellorusso, Milford, MA (US);
Momenta Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present disclosure provides methods for analyzing structure and/or composition of glycoproteins and glycans of glycoproteins. Such methods can include subjecting a glycoprotein preparation to a condition that removes at least one O-linked glycan from the glycoprotein. Such methods can include subjecting a glycoprotein preparation to a condition that releases an N-glycan from the glycoprotein, e.g., prior to subjecting the glycoprotein to a condition that releases an O-glycan from the glycoprotein.