Location History:
- Köln, DE (2008 - 2012)
- Cologne, DE (2011 - 2012)
Company Filing History:
Years Active: 2008-2012
Title: Corinna Thiel: Innovator in Electroporation Technology
Introduction
Corinna Thiel is a prominent inventor based in Kö'ln, Germany. She has made significant contributions to the field of biotechnology, particularly in the area of electroporation. With a total of 5 patents to her name, Thiel's work focuses on methods for introducing biologically active molecules into cells, which has important implications for medical and research applications.
Latest Patents
Thiel's latest patents include a buffer solution for electroporation and a method comprising the use of the same. This method involves introducing biologically active molecules into animal or human cells using an electric current. The process includes suspending the cells and dissolving the biologically active molecules in a buffer solution that contains HEPES and at least 10 mmol·1 magnesium ions (Mg). The buffer solution is designed to have a buffer capacity of at least 20 mmol·1·pH at a change in pH from 7 to 8 and at a temperature of 25°C, with an ionic strength of at least 200 mmol·1. An electric voltage is then applied to the suspension.
Another notable patent is a circuit arrangement for injecting nucleic acids and other biologically active molecules into the nucleus of higher eukaryotic cells using electrical current. This invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eukaryotic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
Career Highlights
Throughout her career, Corinna Thiel has worked with several notable companies, including Lonza Cologne GmbH and Amaxa AG. Her experience in these organizations has allowed her to develop and refine her innovative techniques in biotechnology.
Collaborations
Thiel has collaborated with several professionals in her field, including Gudula Riemen and Meike Weigel. These collaborations have contributed to her success and the advancement of her research.
Conclusion
Corinna Thiel is a distinguished inventor whose work in electroporation technology has the potential to revolutionize the introduction of biologically active molecules into cells. Her innovative patents and collaborations highlight her significant contributions to the field of biotechnology.