Como, Italy

Claudio Giuliano

USPTO Granted Patents = 19 


 

Average Co-Inventor Count = 5.5

ph-index = 3

Forward Citations = 31(Granted Patents)


Company Filing History:


Years Active: 2013-2025

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19 patents (USPTO):

Title: Innovations and Patents of Claudio Giuliano

Introduction

Claudio Giuliano, an accomplished inventor based in Como, Italy, has made significant strides in the field of pharmaceuticals with a notable portfolio of 18 patents. His innovations primarily focus on advancements in drug synthesis and the treatment of various medical conditions.

Latest Patents

Among Claudio's latest patents is a process for the synthesis of substituted chloromethyl dialkylphosphates. This patent discloses compounds, including phosphate and N-oxide prodrugs of the NK1 antagonist netupitant. These compounds are particularly useful in preventing and treating emesis induced by chemotherapy. The methods outlined for manufacturing di-tert-butyl (chloromethyl) phosphate involve a series of chemical reactions that transform dialkylphosphate salts into effective prodrugs.

Another remarkable patent by Claudio is the development of a centrally-active ghrelin agonist. This compound, 3-(1-(2,3-dichloro-4-methoxyphenyl) ethyl)-1-methyl-1-(1,3,3-trimethylpiperidin-4-yl) urea monohydrochloride salt, demonstrates a high ability to cross the blood-brain barrier. It shows considerable efficacy in treating neurotoxic damage and conditions that necessitate a reduction in heart rate. This compound exhibits pharmacological activity at low to moderate doses, indicating a promising therapeutic index.

Career Highlights

Claudio has garnered extensive experience in the pharmaceutical industry, having contributed to innovative projects at Helsinn Healthcare Sa. His work reflects a deep commitment to improving therapeutic options available for patients, particularly in areas that address pressing health needs.

Collaborations

Throughout his career, Claudio has worked alongside esteemed colleagues such as Claudio Pietra and Silvina Garcia Rubio. These collaborations have fostered an environment of shared knowledge and innovation, leading to groundbreaking advancements in their respective fields.

Conclusion

Claudio Giuliano stands out as a significant figure in the landscape of pharmaceutical innovations. With a portfolio of numerous patents and impactful collaborations, his work continues to influence the development of new treatments and enhance the quality of healthcare.

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