The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2018

Filed:

Jun. 28, 2016
Applicant:

Helsinn Healthcare SA, Lugano/Pazzallo, CH;

Inventors:

Luca Fadini, Giubiasco, CH;

Peter Manini, Giubiasco, CH;

Claudio Pietra, Como, IT;

Claudio Giuliano, Como, IT;

Emanuela Lovati, Mendrisio, CH;

Roberta Cannella, Varese, IT;

Alessio Venturini, Varese, IT;

Valentino J Stella, Lawrence, KS (US);

Assignee:

Helsinn Healthcare SA, Lugano/Pazzallo, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/4427 (2006.01); C07D 213/74 (2006.01); C07D 401/04 (2006.01); C07F 9/6509 (2006.01); A61K 31/56 (2006.01); A61K 45/06 (2006.01); C07D 213/89 (2006.01); A61K 31/44 (2006.01); A61K 31/473 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
C07F 9/650952 (2013.01); A61K 31/44 (2013.01); A61K 31/473 (2013.01); A61K 31/496 (2013.01); A61K 31/56 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 213/74 (2013.01); C07D 213/89 (2013.01); C07D 401/04 (2013.01);
Abstract

Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK) receptor. The compounds have the general formula (I):


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