Claudia Kleinlein

Title: Claudia Kleinlein: Innovator in Organometallic Catalysis

Introduction

Claudia Kleinlein is a prominent inventor based in Cambridge, MA (US). She has made significant contributions to the field of organometallic chemistry, particularly in the development of catalysts for C—H bond functionalization.

Latest Patents

Kleinlein holds a patent for "Annulation catalysts via direct C—H bond amination." This patent discloses compounds, methods, reagents, systems, and kits for the preparation and utilization of monomeric or polymeric metal-based compounds. The organometallic catalysts she developed are composed of substituted dipyrrin ligands bound to transition metals. These catalysts enable C—H bond functionalization to yield C—N bonds, generating substituted bicyclic, spiro, and fused nitrogen-containing heterocycles, which are common motifs in various pharmaceutical and bioactive molecules. She has 1 patent to her name.

Career Highlights

Kleinlein is affiliated with Harvard College, where she continues her research and development in the field of catalysis. Her work has garnered attention for its innovative approach to solving complex chemical challenges.

Collaborations

Kleinlein has collaborated with notable colleagues, including Theodore Alexander Betley and Alexandre Mikhailine, contributing to advancements in their shared field of study.

Conclusion

Claudia Kleinlein is a trailblazer in organometallic catalysis, with her innovative patent paving the way for future research and applications in chemistry. Her contributions are vital to the ongoing development of effective catalysts in the pharmaceutical industry.