The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2024

Filed:

Sep. 19, 2019
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Theodore Alexander Betley, Cambridge, MA (US);

Alexandre Mikhailine, Cambridge, MA (US);

Claudia Kleinlein, Cambridge, MA (US);

Yuyang Dong, Cambridge, MA (US);

Yunjung Baek, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 31/18 (2006.01); B01J 31/22 (2006.01); C07D 207/06 (2006.01); C07D 209/04 (2006.01); C07D 209/44 (2006.01); C07D 209/54 (2006.01); C07D 211/70 (2006.01); C07D 263/04 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
B01J 31/1815 (2013.01); B01J 31/2243 (2013.01); C07D 207/06 (2013.01); C07D 209/04 (2013.01); C07D 209/44 (2013.01); C07D 209/54 (2013.01); C07D 211/70 (2013.01); C07D 263/04 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 487/08 (2013.01); B01J 2231/4283 (2013.01); B01J 2531/0216 (2013.01); B01J 2531/842 (2013.01); B01J 2531/845 (2013.01); B01J 2531/847 (2013.01); B01J 2540/66 (2013.01);
Abstract

Disclosed are compounds, methods, reagents, systems, and kits for the preparation and utilization of monomeric or polymeric metal-based compounds. These metal-based compounds are organometallic catalysts composed of substituted dipyrrin ligands bound to transition metals. C—H bond functionalization catalysis can be performed with the disclosed organometallic catalysts to yield C—N bonds to generate substituted bicyclic, spiro, and fused nitrogen-containing heterocycles, all common motifs in various pharmaceutical and bioactive molecules.


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