Company Filing History:
4 out of 257 
2 out of 11 Years Active: 2017-2023
Title: Innovations by Inventor Chuang Xie
Introduction
Chuang Xie, an accomplished inventor located in Tianjin, China, has made significant contributions to the field of pharmaceuticals and crystallization processes. With a portfolio of 4 patents, his inventions reflect a deep understanding of chemical interactions and material properties, particularly in the context of drug solubility and formulation.
Latest Patents
Among Chuang Xie's latest patents are two notable innovations:
1. **Crystalline form of phenyl bis (2,4,6-trimethylbenzoyl) phosphine oxide with large particle size and crystallization method for making same**: This patent presents a new crystalline form of phenyl bis (2,4,6-trimethylbenzoyl) phosphine oxide that exhibits a larger particle size. The crystalline form belongs to a triclinic crystal system and space group P-1. The crystallization method involves adding a solid form of the compound to a solvent, dissolving it through controlled heating, cooling, and subsequently using an anti-solvent to precipitate the crystals. The optimized process includes specific time durations for crystal growth, culminating in a filtered and dried crystalline product.
2. **Etoricoxib solvates and preparation method thereof**: This invention pertains to etoricoxib solvates and their effective preparation methods. Utilizing solvents classified as hydrogen bond donors or acceptors, the process allows for the synthesis of etoricoxib solvates that demonstrate high thermal stability, unique crystal forms, and improved solubility features in comparison to the original drug. The efficient method leading to high molar yields exceeds 90%, highlighting both time and energy efficiency during preparation.
Career Highlights
Chuang Xie has been affiliated with distinguished institutions such as Tianjin University and Hainan Lingkang Pharmaceutical Co., Ltd. His work reflects the intersection of advanced academic research and practical pharmaceutical applications, guiding his efforts towards innovations that enhance drug delivery and efficacy.
Collaborations
Throughout his career, Chuang Xie has collaborated with key professionals, including Baohong Hou and Ying Bao. These partnerships have fostered a rich environment for innovation and have contributed to the successful development of his patented technologies.
Conclusion
Chuang Xie continues to be a valuable contributor to the fields of crystallization and pharmaceutical development. Through his innovative patents and collaborations, he stands at the forefront of enhancing the properties and applications of chemical compounds, particularly in improving drug solubility and stability. His work not only reflects personal achievement but also serves as a bridge between academic research and real-world medical solutions.