The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2017
Filed:
Aug. 25, 2017
Tianjin University, Tianjin, CN;
Hainan Lingkang Pharmaceutical Co., Ltd, Haikou, CN;
Hongxun Hao, Tianjin, CN;
Linggang Tao, Haikou, CN;
Fang He, Tianjin, CN;
Baohong Hou, Tianjin, CN;
Jingkang Wang, Tianjin, CN;
Jun Lv, Hainan, CN;
Qiuxiang Yin, Tianjin, CN;
Yongli Wang, Tianjin, CN;
Junbo Gong, Tianjin, CN;
Chuang Xie, Tianjin, CN;
Ying Bao, Tianjin, CN;
TIANJIN UNIVERSITY, Tianjin, CN;
HAINAN LINGKANG PHARMACEUTICAL CO., LTD, Haikou, CN;
Abstract
A novel crystalline form is defined by diffraction angle 2θ° of X-ray powder diffraction pattern and characteristic peak of differential scanning calorimetry (DSC). The novel crystalline form of Cefamandole Nafate is prepared as follows: adding Cefamandole Nafate in solid state to an organic solvent to form a suspension with a concentration of 0.04˜0.3 g/ml, stirring the suspension at 40˜50° C. for a period of time, and then cooling to 5˜15° C. at certain cooling rate, continuing to stir for a period of time, then suction filtrating the obtained suspension, the resulting filer cake is Cefamandole Nafate as wet product, which is dried to constant weight to provide the novel crystalline form of Cefamandole Nafate as final product.