The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2017
Filed:
Nov. 20, 2015
Tianjin University, Tianjin, CN;
Hainan Lingkang Pharmaceutical Co., Ltd, Haikou, CN;
Hongxun Hao, Tianjin, CN;
Linggang Tao, Haikou, CN;
Zhihong Sun, Tianjin, CN;
Baohong Hou, Tianjin, CN;
Jun Lv, Haikou, CN;
Qiuxiang Yin, Tianjin, CN;
Yongli Wang, Tianjin, CN;
Junbo Gong, Tianjin, CN;
Chuang Xie, Tianjin, CN;
Ying Bao, Tianjin, CN;
TIANJIN UNIVERSITY, Tianjin, CN;
HAINAN LINGKANG PHARMACEUTICAL CO., LTD, Haikou, CN;
Abstract
A novel crystalline form of Cefathiamidine compound and its preparation method, characterizing in its X-ray powder diffraction pattern and differential scanning calorimetry thermogram. Dissolving Cefathiamidine compound with a purity of 98% or higher in a solvent at a temperature of 30˜45° C. to form a solution, whose concentration is controlled within 0.05˜0.2 g/mL, and then adding a solventing-out agent to the solution, wherein the amount of the solventing-out agent is 3˜5 times (in volume) of that of the solvent; followed by cooling the solution down to 0˜10° C. at a rate of 0.2˜1° C./min; continuing to stir for 1˜3 hours, and separating the obtained solid-liquid suspension to provide a novel crystalline form of Cefathiamidine compound after drying.