Company Filing History:
2 out of 622 
1 out of 4,945 
1 out of 168 
Years Active: 1996-2009
Title: Innovations of Christopher Lim Sigua
Introduction
Christopher Lim Sigua is an accomplished inventor based in Antioch, CA (US). He holds a total of 4 patents that showcase his contributions to the field of molecular biology. His work primarily focuses on the development of advanced DNA polymerases, which are essential for various DNA synthesis applications.
Latest Patents
One of his notable patents is for thermostable DNA polymerases incorporating nucleoside triphosphates labeled with fluorescent dyes. These modified thermostable DNA polymerases exhibit enhanced efficiency for incorporating unconventional nucleotides, particularly those labeled with fluorescein family dyes. Such enzymes are particularly advantageous in many in vitro DNA synthesis applications. They are especially useful in chain termination nucleic acid sequencing protocols, similar to native forms of these enzymes. The genes encoding the modified enzymes, along with methods for their production and use, offer significant cost and efficiency advantages for DNA sequencing.
Career Highlights
Christopher has worked with prominent companies in the biotechnology sector, including Roche Molecular Systems, Inc. and Hoffmann-La Roche Inc. His experience in these organizations has contributed to his expertise in developing innovative solutions in molecular biology.
Collaborations
Throughout his career, Christopher has collaborated with esteemed colleagues such as David H. Gelfand and Thomas W. Myers. These collaborations have further enriched his work and expanded the impact of his inventions.
Conclusion
Christopher Lim Sigua is a significant figure in the field of molecular biology, with a focus on enhancing DNA synthesis technologies. His innovative patents and collaborations reflect his commitment to advancing scientific research and applications.