Christopher Gordon Tate

Title: Christopher Gordon Tate: A Pioneer in Mutant G-Protein Coupled Receptors

Introduction

Christopher Gordon Tate is a distinguished inventor based in Cambridge, GB, known for his significant contributions to the field of molecular biology. With a remarkable portfolio of ten patents, his work primarily focuses on developing mutant G-protein coupled receptors that exhibit enhanced conformational stability. This innovative research has the potential to lead to breakthroughs in various therapeutic areas.

Latest Patents

Among his latest patents, Tate's work on mutant G-protein coupled receptors stands out. This invention relates to polynucleotides that encode these mutated receptors, which can be utilized in various applications. The patent also covers methods of preparing crystallized forms of these receptors, showcasing Tate's innovative approach to enhancing protein stability. Additionally, one of his patents presents a mutant of a parent heterotrimeric G protein alpha (Gα) subunit, specifically designed to bind to a GPCR independently of Gβ and Gγ subunits. This unique mutant contains specific amino acid sequence mutations, including deletions, substitutions, and insertions, further advancing the understanding of G-protein functions.

Career Highlights

Christopher Gordon Tate has worked with notable organizations such as Heptares Therapeutics Limited and the Medical Research Council. His tenure at these institutions has not only honed his expertise in the field but also contributed to substantial advancements in biopharmaceutical research. His ten patents reflect his innovative spirit and commitment to improving therapeutic solutions.

Collaborations

Throughout his career, Tate has collaborated with esteemed colleagues, including Richard Henderson and Antony Johannes Warne. These collaborations have enriched his research and facilitated the development of groundbreaking technologies in the domain of G-protein coupled receptors.

Conclusion

Christopher Gordon Tate's inventive work in the field of mutant G-protein coupled receptors marks him as a prominent figure in contemporary scientific research. With numerous patents to his name and a strong foundation built on collaboration and innovation, Tate continues to influence the landscape of molecular biology and pharmaceutical research. His contributions are paving the way for new therapeutic strategies that could significantly benefit human health.