The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
May. 11, 2020
Heptares Therapeutics Limited, Cambridge, GB;
Richard Henderson, Cambridge, GB;
Christopher Gordon Tate, Cambridge, GB;
Francesca Magnani, Cambridge, GB;
Maria Josefa Serrano-Vega, Cambridge, GB;
Yoko Shibata, Cambridge, GB;
Antony Johannes Warne, Cambridge, GB;
Malcolm Peter Weir, Cambridge, GB;
Heptares Therapeutics Limited, Cambridge, GB;
Abstract
The invention relates to mutant G-protein coupled receptors with increased conformational stability, and methods of use thereof. In some aspects, polynucleotides encoding the mutant G-protein coupled receptors are provided. In some aspects, host cells comprising the polynucleotides are provided. In some aspects, the invention relates to crystallized forms of the mutant G-protein coupled receptors, and methods of preparing the same.