Antony Johannes Warne

Title: Antony Johannes Warne: Innovator in G-Protein Coupled Receptors

Introduction

Antony Johannes Warne is a prominent inventor based in Cambridge, GB. He has made significant contributions to the field of biochemistry, particularly in the area of G-protein coupled receptors (GPCRs). With a total of 5 patents to his name, Warne's work has advanced our understanding of these critical proteins.

Latest Patents

Warne's latest patents include groundbreaking inventions related to mutant G-protein coupled receptors. One notable patent focuses on mutant GPCRs with increased conformational stability and methods for selecting them. This invention provides polynucleotides encoding the mutant GPCRs and host cells that comprise these polynucleotides. Additionally, it covers crystallized forms of the mutant GPCRs and methods for their preparation. Another significant patent involves a mutant of a parent heterotrimeric G protein alpha (Gα) subunit, which is capable of binding to a GPCR without the need for G protein beta (Gβ) and gamma (Gγ) subunits. This mutant contains one or more mutations compared to the parent Gα subunit, which may include deletions, substitutions, or insertions.

Career Highlights

Antony Warne is currently associated with Heptares Therapeutics Limited, where he continues to innovate in the field of GPCR research. His work has been instrumental in developing new methods and applications that enhance our understanding of these receptors and their functions.

Collaborations

Warne has collaborated with notable scientists in his field, including Christopher Gordon Tate and Richard Henderson. These collaborations have further enriched his research and contributed to the advancement of biochemistry.

Conclusion

Antony Johannes Warne is a distinguished inventor whose work on G-protein coupled receptors has made a significant impact in the field of biochemistry. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and technology.