Christopher D Ferris

Title: The Innovative Contributions of Christopher D. Ferris

Introduction

Christopher D. Ferris, based in Franklin, TN, is an accomplished inventor with a remarkable portfolio comprising four patents. His innovative work primarily centers around biochemistry, specifically in the areas of protein assays and neurobiology. Ferris's contributions have significant implications for understanding various biological processes and potential treatments for neurological conditions.

Latest Patents

One of his notable patents is titled "Method for Assaying Protein Nitrosylation." This method addresses the detection of proteins containing nitrosothiols, a direct modification of cysteine residues mediated by nitric oxide. The procedure involves converting nitrosylated cysteines into tagged cysteines, allowing for their detection through immunoblotting or purification via affinity chromatography. This method can be applied to both in vitro S-nitrosylation and the detection of endogenous S-nitrosothiols in specific protein substrates.

Another significant patent is for "Mammalian Serine Racemase," an enzyme crucial for converting L-serine to D-serine in the mammalian brain. This enzyme plays a critical role as an endogenous ligand for the glycine site of NMDA receptors. Ferris and his team identified a soluble enzyme from rat brain that is selectively active toward L-serine and requires pyridoxal 5'-phosphate. The potential therapeutic applications of modulators for this racemase can aid in addressing overstimulation of NMDA receptors associated with conditions like stroke and neurodegenerative diseases.

Career Highlights

Ferris has made substantial contributions to the field of biochemistry through his association with prestigious organizations. He has worked at The Johns Hopkins University, a renowned institution known for its exceptional research and innovation. Additionally, he has contributed to advancements in cancer research at Memorial Sloan Kettering Cancer Center, further demonstrating his commitment to scientific exploration and discovery.

Collaborations

Throughout his career, Ferris has collaborated with distinguished scientists, including Solomon H. Snyder and Samie R. Jaffrey. These partnerships have enriched his research endeavors and expanded the impact of his innovative findings in the scientific community.

Conclusion

Christopher D. Ferris stands out as a prominent inventor whose work significantly contributes to the understanding of protein interactions and neurological processes. His patents reflect a commitment to advancing science and improving clinical outcomes, making him a valuable asset to the fields of biochemistry and neurobiology. As he continues to explore the complexities of these domains, his contributions will undoubtedly inspire further innovations and discoveries.