Christine Menetrier-Caux

Title: Christine Menetrier-Caux: Innovator in Immunology

Introduction

Christine Menetrier-Caux is a prominent inventor based in Lyons, France, known for her significant contributions to the field of immunology. With a total of nine patents to her name, she has made remarkable advancements in the understanding and treatment of various diseases, particularly in cancer therapy.

Latest Patents

Among her latest patents is a groundbreaking invention involving antibodies directed against ICOS. This invention provides antibodies that neutralize ICOS engagement on Treg, inhibiting the fixation between ICOS and ICOS-L, and abrogating the proliferation of Treg induced by plasmacytoid dendritic cells. Additionally, these antibodies induce IL-10 and IFN-γ production, promote CD4- T cell proliferation, reduce Tconv proliferation, and enhance the immunosuppressive function of Treg. Another notable patent involves CD73 blocking agents, which are antibodies that bind and inhibit CD73, increasing T cell proliferation in the presence of CD39-expressing B cells and ATP. This invention also encompasses methods for diagnosing, treating, or preventing cancer.

Career Highlights

Christine has worked with esteemed organizations such as the Institut National de la Santé et de la Recherche Médicale and the Centre Léon Bérard. Her work in these institutions has been pivotal in advancing cancer research and immunotherapy.

Collaborations

Throughout her career, Christine has collaborated with notable colleagues, including Daniel Olive and Christophe Caux. These partnerships have further enriched her research and contributed to her innovative work in immunology.

Conclusion

Christine Menetrier-Caux stands out as a leading inventor in the field of immunology, with her patents paving the way for new therapeutic approaches in cancer treatment. Her dedication to research and innovation continues to inspire advancements in medical science.