The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 2021

Filed:

Oct. 11, 2016
Applicants:

Innate Pharma, Marseilles, FR;

Centre Leon Berard, Lyons, FR;

Inventors:

Christophe Caux, Bressolles, FR;

Laurent Gauthier, Marseilles, FR;

Nicolas Gourdin, Marseilles, FR;

Christine Menetrier-Caux, Bressolles, FR;

Carine Paturel, Marcy l'Etoile, FR;

Ivan Perrot, Cassis, FR;

Assignees:

INNATE PHARMA, Marseilles, FR;

CENTRE LÉON BÉRARD, Lyons, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/40 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61P 35/00 (2018.01); C07K 16/40 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/74 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided are antibodies that bind and inhibit CD73, are capable of increasing the proliferation of T cells in the presence of CD39-expressing B cells and ATP. The invention also relates to cells producing such compounds; methods of making such compounds, and antibodies, fragments, variants, and derivatives thereof; pharmaceutical compositions comprising the same; methods of using the compounds to diagnose, treat or prevent cancer.


Find Patent Forward Citations

Loading…