Taipei, Taiwan

Chin-Tarng Lin

USPTO Granted Patents = 6 

 

Average Co-Inventor Count = 2.9

ph-index = 1

Forward Citations = 6(Granted Patents)


Company Filing History:


Years Active: 2007-2019

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6 patents (USPTO):Explore Patents

Title: Innovations in Cancer Treatment by Chin-Tarng Lin

Introduction

Chin-Tarng Lin is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of cancer research, holding a total of 6 patents. His work focuses on developing innovative peptide-based methods for the diagnosis and treatment of cancer.

Latest Patents

One of his latest patents involves peptides for the diagnosis and treatment of cancer. This method describes a peptide histochemical diagnosis to detect peptide binding proteins in cancer tissue. The peptide specifically binds to tumor cells and is linked to dextran-coated iron oxide nanoparticles. This innovative approach allows for binding to formalin-fixed and paraffin-embedded tumor surgical specimens, enabling the evaluation of peptide-targeted chemotherapy efficacy for cancer patients.

Another significant patent addresses peptides specific for hepatocellular carcinoma (HCC) cells. HCC is the fourth leading cause of cancer death worldwide. Lin's research utilized phage display to identify novel peptides, including SP94, which binds specifically to HCC cells. In vitro studies showed that the phage clone PC94 binds to HCC cell lines, while in vivo studies demonstrated that PC94 homed specifically to tumor tissues in SCID mice bearing human HCC xenografts. The conjugation of SP94 with liposomal doxorubicin enhanced therapeutic efficacy against HCC xenografts, indicating that SP94 can improve systemic treatment for patients with advanced HCC.

Career Highlights

Chin-Tarng Lin has worked with esteemed institutions such as National Taiwan University and Academia Sinica. His research has significantly advanced the understanding of cancer treatment methodologies.

Collaborations

Lin has collaborated with notable colleagues, including Han-Chung Wu and Tong-Young Lee, contributing to the advancement of cancer research through teamwork and shared expertise.

Conclusion

Chin-Tarng Lin's innovative work in peptide-based cancer diagnosis and treatment showcases his dedication to improving patient outcomes. His contributions to the field are invaluable and continue to inspire future research in oncology.

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