The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2019
Filed:
Apr. 26, 2017
Applicant:
National Taiwan University, Taipei, TW;
Inventors:
Chin-Tarng Lin, Taipei, TW;
Han-Chung Wu, Taipei, TW;
Assignee:
NATIONAL TAIWAN UNIVERSITY, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/00 (2006.01); A61K 47/64 (2017.01); A61K 51/08 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); C07K 14/005 (2006.01); A61K 39/395 (2006.01); C07H 21/04 (2006.01); C12N 5/07 (2010.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 38/16 (2013.01); A61K 39/395 (2013.01); A61K 51/088 (2013.01); C07H 21/04 (2013.01); C07K 7/06 (2013.01); C12N 5/06 (2013.01); A61K 38/00 (2013.01); C12N 9/00 (2013.01);
Abstract
A method of peptide histochemical diagnosis to detect the peptide binding protein in the cancer tissue is described. This peptide binding specifically to tumor cells is linked to the dextran coated iron oxide nanoparticle. The peptide linked dextran coated iron oxide nanoparticle can be used to bind to the formalin-fixed and paraffin-embedded tumor surgical specimens, and the method of present disclosure can be used to evaluate the efficacy of peptide-targeted chemotherapy for treatment of cancer patients.