Chi-Li Chen

Chi-Li Chen is a prominent inventor based in Newton, MA (US). She has made significant contributions to the field of biotechnology, particularly in the development of novel methods for protein degradation and pharmaceutical compositions. With a total of 9 patents to her name, her work has the potential to impact various medical applications.

Latest Patents

One of Chi-Li Chen's latest patents focuses on N/O-linked degrons and degronimers for protein degradation. This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein selected for in vivo degradation. The invention also includes methods of use and compositions, as well as methods for their preparation. Additionally, it offers Degrons that can be utilized to treat disorders mediated by cereblon or an Ikaros family protein. Another significant patent involves crystalline forms of eravacycline, which relates to the bis-HCl salt of a compound represented by Structural Formula 1. This invention includes pharmaceutical compositions comprising these crystalline forms, which can be used to treat various disorders.

Career Highlights

Throughout her career, Chi-Li Chen has worked with notable companies such as Tetraphase Pharmaceuticals, Inc. and C4 Therapeutics, Inc. Her expertise in the field has allowed her to contribute to groundbreaking research and development efforts.

Collaborations

Chi-Li Chen has collaborated with esteemed colleagues, including Minsheng He and Andrew John Phillips. These partnerships have further enhanced her innovative work and expanded the impact of her inventions.

Conclusion

Chi-Li Chen's contributions to biotechnology and her innovative patents demonstrate her commitment to advancing medical science. Her work continues to pave the way for new treatments and therapies that can benefit patients worldwide.

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