The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2022
Filed:
Dec. 19, 2019
C4 Therapeutics, Inc., Watertown, MA (US);
Andrew J. Phillips, Arlington, VA (US);
Christopher G. Nasveschuk, Stoneham, MA (US);
James A. Henderson, Weston, MA (US);
Yanke Liang, Belmont, MA (US);
Minsheng He, Andover, MA (US);
Martin Duplessis, Somerville, MA (US);
Chi-Li Chen, Newton, MA (US);
C4 Therapeutics, Inc., Watertown, MA (US);
Abstract
This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.