Company Filing History:
Years Active: 2021-2023
Title: Innovations of Chenyu Li in DNA Sequencing and Pathogen Detection
Introduction
Chenyu Li is a prominent inventor based in Hayward, California, known for his significant contributions to the fields of DNA sequencing and pathogen detection. With a total of two patents to his name, Li has developed innovative methods that enhance the accuracy and efficiency of genetic analysis.
Latest Patents
Li's latest patents include groundbreaking technologies such as "Methods and compositions for amplifying DNA and generating DNA sequencing results from target-enriched DNA molecules" and "High throughput detection of pathogen RNA in clinical specimens." The first patent, referred to as SubDivision-Seq, involves a two-part process. The initial phase focuses on creating a target-enriched DNA library, organizing unique molecular identifiers (UMIs) on DNA molecules to form primary clones, and subdividing these clones into subclones. The second phase entails sequencing the DNA library using next-generation sequencing (NGS) and deducing consensus sequences from each subclone and primary clone. His second patent provides laboratory-based high throughput methods for detecting pathogen mRNA, specifically targeting SARS-CoV-2 RNA from up to 85,000 samples in a single Illumina NovaSeq sequencing run. This method includes barcoding cDNA and utilizing automatic liquid handling, resulting in a cost-effective and rapid assay.
Career Highlights
Chenyu Li is currently employed at Paragon Genomics, Inc., where he continues to push the boundaries of genetic research. His work has been instrumental in developing technologies that not only improve sequencing accuracy but also facilitate rapid pathogen detection, which is crucial in clinical settings.
Collaborations
Li collaborates with notable colleagues such as Zhitong Liu and David Debruyne, contributing to a dynamic research environment that fosters innovation and advancement in genetic technologies.
Conclusion
Chenyu Li's contributions to DNA sequencing and pathogen detection exemplify the impact of innovative thinking in the field of genetics. His patents reflect a commitment to enhancing scientific methodologies, ultimately benefiting both research and clinical applications.