The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2021

Filed:

May. 20, 2020
Applicant:

Paragon Genomics, Inc., Hayward, CA (US);

Inventors:

Zhitong Liu, Foster City, CA (US);

Chenyu Li, Hayward, CA (US);

David Debruyne, Foster City, CA (US);

Guoying Liu, San Ramon, CA (US);

Assignee:

Paragon Genomics, Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/70 (2006.01); C12Q 1/6874 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/701 (2013.01); C12N 15/1013 (2013.01); C12N 15/1096 (2013.01); C12Q 1/6874 (2013.01);
Abstract

Laboratory-based high throughput methods and compositions (e.g., kits) for the detection of pathogen mRNA, including in particular, for the detection of SARS-CoV-2 RNA from up to 85,000 samples in one Illumina NovaSeq sequencing run. These methods may include barcoding cDNA, indexing pools of libraries and intensive use of automatic liquid handling, providing a ready-to-sequence library mix. These methods and compositions may allow a very inexpensive per sample cost and an assay that may be performed in about one day or less.


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