Company Filing History:
Years Active: 2018-2021
Title: Innovations by Guoying Liu in Pathogen Detection
Introduction
Guoying Liu is an accomplished inventor based in San Ramon, CA, known for his significant contributions to the field of pathogen detection. With a total of three patents to his name, Liu has developed innovative methods that enhance the efficiency and accuracy of detecting pathogens in clinical specimens.
Latest Patents
One of Liu's latest patents focuses on high throughput detection of pathogen RNA in clinical specimens. This laboratory-based method allows for the detection of SARS-CoV-2 RNA from up to 85,000 samples in a single Illumina NovaSeq sequencing run. The approach includes barcoding cDNA, indexing pools of libraries, and utilizing automatic liquid handling, resulting in a ready-to-sequence library mix. This innovation not only reduces the cost per sample but also enables assays to be performed in about one day or less. Another notable patent involves methods and compositions for reducing non-specific amplification products. This invention aims to improve the amplification of target-specific products by minimizing non-specific amplification, such as primer-dimers, when amplifying multiple nucleotide regions. The described methods may include resolvases that recognize and bind to aberrant DNA structures, enhancing the overall efficiency of the amplification process.
Career Highlights
Guoying Liu is currently employed at Paragon Genomics, Inc., where he continues to push the boundaries of innovation in genomic technologies. His work has been instrumental in developing solutions that address critical challenges in pathogen detection and amplification.
Collaborations
Liu collaborates with talented individuals in his field, including Zhitong Liu and Jeffrey Juehui Liu, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Guoying Liu's contributions to pathogen detection through his innovative patents demonstrate his commitment to advancing medical technology. His work not only enhances the efficiency of clinical testing but also plays a crucial role in public health initiatives.