Company Filing History:
Years Active: 1998-2019
Title: The Innovative Contributions of Charles J Sherr
Introduction
Charles J Sherr is a prominent inventor based in Memphis, TN, known for his significant contributions to cancer research and treatment. With a total of 12 patents to his name, Sherr has made remarkable strides in the field of molecular biology and oncology. His work focuses on understanding the mechanisms of cancer and developing targeted therapies.
Latest Patents
Among his latest patents is a method and kits for identifying CDK9 inhibitors for the treatment of cancer. This innovative method involves determining the presence of overexpression of MYC in a biological sample from a patient suffering from cancer. The presence of MYC overexpression indicates sensitivity to treatment by a CDK9 inhibitor, particularly in cancers such as carcinoma, leukemia, and lymphoma. Another notable patent is related to the Cyclin D binding factor and its uses. This invention reveals a direct interaction between D-type cyclins and a novel myb-like transcription factor, DMP1. The findings suggest that D-type cyclins regulate gene expression in an RB-independent manner, providing insights into cancer biology.
Career Highlights
Charles J Sherr has had a distinguished career, working at renowned institutions such as St. Jude Children's Research Hospital and Cold Spring Harbor Laboratory. His research has significantly advanced the understanding of cancer mechanisms and therapeutic approaches.
Collaborations
Throughout his career, Sherr has collaborated with notable colleagues, including Dawn E Quelle and Hiroshi Hirai. These collaborations have further enriched his research and contributed to the development of innovative cancer treatments.
Conclusion
Charles J Sherr's contributions to cancer research through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to impact the development of targeted therapies for cancer patients.