Franklin, TN, United States of America

Charles David Weaver

USPTO Granted Patents = 16 

 

Average Co-Inventor Count = 3.0

ph-index = 6

Forward Citations = 100(Granted Patents)


Location History:

  • Franklin, TN (US) (2011 - 2018)
  • Nashville, TN (US) (2015 - 2022)

Company Filing History:


Years Active: 2011-2022

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16 patents (USPTO):Explore Patents

Title: Charles David Weaver: Innovator in Thallium Sensor Technology

Introduction

Charles David Weaver is a prominent inventor based in Franklin, TN (US). He has made significant contributions to the field of sensor technology, particularly in the development of thallium sensors for high-throughput screening of potassium channels. With a total of 16 patents to his name, Weaver's work has advanced the understanding and application of fluorescent sensors in various scientific fields.

Latest Patents

Weaver's latest patents include innovative rhodol-based thallium sensors designed for high-throughput screening of potassium channels. These novel compounds feature a rhodol fluorophore attached to an amino dicarboxylic acid metal binding moiety. The preparation method allows for the compounds to be utilized in Tlflux assays, providing a more red-shifted and less pH-sensitive alternative to existing sensors. Another significant patent involves pro-fluorophore compounds, specifically N,N'-diacyl rhodamine compounds, which can be converted to rhodamine by porcine liver esterase (PLE) to produce a fluorescence signal. These compounds have potential applications as substrates in enzymatic assays or as labels in cellular imaging.

Career Highlights

Throughout his career, Charles David Weaver has worked with esteemed institutions such as Vanderbilt University and Meharry Medical College. His research has focused on the intersection of chemistry and biology, leading to advancements in sensor technology that have broad implications for scientific research and medical diagnostics.

Collaborations

Weaver has collaborated with notable colleagues, including P Jeffrey Conn and Craig William Lindsley. These partnerships have fostered a collaborative environment that enhances the innovation process and leads to groundbreaking discoveries in the field.

Conclusion

Charles David Weaver's contributions to thallium sensor technology exemplify the impact of innovative thinking in scientific research. His patents and collaborations continue to influence the development of advanced sensor systems, paving the way for future discoveries.

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