The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 2021

Filed:

Mar. 26, 2019
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Gary A. Sulikowski, Nashville, TN (US);

Kristopher K. Abney, Nashville, TN (US);

Susan J. Ramos-Hunter, Nashville, TN (US);

Ian M. Romaine, Nashville, TN (US);

Charles David Weaver, Nashville, TN (US);

Assignees:

Vanderbilt University, Nashville, TN (US);

Meharry Medical College, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/06 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C12P 17/06 (2013.01); G01N 33/582 (2013.01);
Abstract

Provided are N,N'-diacyl rhodamine compounds, which may be converted to rhodamine by porcine liver esterase (PLE) to produce a fluorescence signal. These compounds may be used, for example, as substrates in enzymatic assays or as labels in cellular imaging.


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