The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2013

Filed:

Sep. 17, 2010
Applicants:

P. Jeffrey Conn, Brentwood, TN (US);

Craig W. Lindsley, Brentwood, TN (US);

Kyle A. Emmitte, Spring Hill, TN (US);

Charles David Weaver, Franklin, TN (US);

Alice L. Rodriguez, Nashville, TN (US);

Andrew S. Felts, Nashville, TN (US);

Carrie K. Jones, Nashville, TN (US);

Brittney S. Bates, Nashville, TN (US);

Inventors:

P. Jeffrey Conn, Brentwood, TN (US);

Craig W. Lindsley, Brentwood, TN (US);

Kyle A. Emmitte, Spring Hill, TN (US);

Charles David Weaver, Franklin, TN (US);

Alice L. Rodriguez, Nashville, TN (US);

Andrew S. Felts, Nashville, TN (US);

Carrie K. Jones, Nashville, TN (US);

Brittney S. Bates, Nashville, TN (US);

Assignee:

Vanderbilt University, Nashville, TN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 213/65 (2006.01); A61P 29/00 (2006.01); A61P 25/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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