Ann Arbor, MI, United States of America

Charles A Cain

USPTO Granted Patents = 26 


 

Average Co-Inventor Count = 3.0

ph-index = 16

Forward Citations = 1,389(Granted Patents)


Company Filing History:

goldMedal25 out of 3,370 
 
University of Michigan
 patents
silverMedal4 out of 24 
 
Histosonics, Inc.
 patents
bronzeMedal1 out of 832,680 
Other
 patents
where one patent can have more than one assignee

Years Active: 1997-2025

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26 patents (USPTO):Explore Patents

Title: Innovations in Medical Technology: The Contributions of Charles A. Cain

Introduction

Charles A. Cain is a prominent inventor based in Ann Arbor, Michigan, known for his significant contributions to the field of medical technology. With a total of 24 patents to his name, Cain has made substantial advancements in ultrasound therapies, particularly focusing on innovative techniques for treating brain tissue and thrombolysis.

Latest Patents

Among Cain's latest innovations are his patents related to histotripsy therapy systems and methods for the treatment of brain tissue. One notable invention includes a histotripsy therapy system designed to treat brain tissue, which features an ultrasound therapy transducer, a drainage catheter, and a variety of piezoelectric sensors positioned within the catheter. This system works by transmitting ultrasound pulses into the brain, creating cavitation that liquefies targeted brain tissues. Additionally, it employs an aberration correction algorithm to counteract the effects of ultrasound pulses passing through a patient's skullcap.

Another significant patent pertains to histotripsy for thrombolysis. This non-invasive method utilizes ultrasound to perform thrombolysis by focusing high-intensity ultrasound beams onto blood clots or other vascular occlusions. The innovative approach can apply various mechanisms like cavitational, sonochemical, mechanical fractionation, or thermal processes to effectively ablate and dissolve clots, which could include conditions such as deep vein thrombosis and pulmonary embolus.

Career Highlights

Cain has spent part of his career at major institutions such as the University of Michigan and Histosonics, Inc., where he has played a pivotal role in advancing the understanding and application of ultrasound technology in medicine. His work has been instrumental in translating complex scientific principles into practical medical solutions that improve patient outcomes.

Collaborations

Throughout his career, Cain has collaborated with esteemed professionals like Zhen Xu and Adam D. Maxwell. These collaborations have contributed to the successful development and implementation of his patented technologies, showcasing the importance of teamwork in advancing medical innovations.

Conclusion

Charles A. Cain's work exemplifies the essence of innovation in the medical field, particularly in ultrasound therapy. His contributions not only highlight the potential of new technologies in treating complex medical conditions but also underscore the vital role of inventors and research collaborations in pioneering advancements that can enhance healthcare delivery. With a diverse portfolio of patents, Cain continues to inspire future generations of innovators in medical technology.

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