The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Jun. 05, 2023
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Adam D. Maxwell, Ann Arbor, MI (US);

Zhen Xu, Ann Arbor, MI (US);

Hitinder S. Gurm, Ann Arbor, MI (US);

Charles A. Cain, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/22 (2006.01); A61B 5/0536 (2021.01); A61B 5/055 (2006.01); A61B 8/00 (2006.01); A61B 8/08 (2006.01); A61B 17/00 (2006.01); A61B 17/225 (2006.01); A61B 90/00 (2016.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/22004 (2013.01); A61B 17/2258 (2013.01); A61M 37/0092 (2013.01); A61B 5/0536 (2013.01); A61B 5/055 (2013.01); A61B 8/00 (2013.01); A61B 8/08 (2013.01); A61B 8/485 (2013.01); A61B 2017/00154 (2013.01); A61B 2017/00172 (2013.01); A61B 2017/00778 (2013.01); A61B 2017/22001 (2013.01); A61B 2017/22008 (2013.01); A61B 2017/22088 (2013.01); A61B 2017/22089 (2013.01); A61B 2090/378 (2016.02);
Abstract

Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as 'Thrombolysis.'


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