The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2021

Filed:

Sep. 22, 2017
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Zhen Xu, Ann Arbor, MI (US);

Ryan M. Miller, Ann Arbor, MI (US);

Adam D. Maxwell, Ann Arbor, MI (US);

Charles A. Cain, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61B 17/22 (2006.01); A61B 17/225 (2006.01); A61B 8/00 (2006.01); A61B 5/00 (2006.01); G01S 15/89 (2006.01);
U.S. Cl.
CPC ...
A61B 8/488 (2013.01); A61B 5/4848 (2013.01); A61B 8/54 (2013.01); A61B 17/22012 (2013.01); A61B 17/2258 (2013.01); G01S 15/899 (2013.01); G01S 15/8979 (2013.01); A61B 5/0035 (2013.01); A61B 5/0059 (2013.01); A61B 5/0075 (2013.01); A61B 8/543 (2013.01); G01S 15/8981 (2013.01);
Abstract

A Histotripsy therapy system is provided that can include any number of features. In some embodiments, the system includes a high voltage power supply, a pulse generator electrically coupled to at least one signal switching amplifier, at least one matching network electrically coupled to the signal switching amplifier(s), and an ultrasound transducer having at least one transducer element. The Histotripsy therapy system can further include an ultrasound Doppler imaging system. The Doppler imaging system and the Histotripsy therapy system can be synchronized to enable color Doppler acquisition of the fractionation of tissue during Histotripsy therapy. Methods of use are also described.


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