Location History:
- Tamil Nadu, IN (2011)
- Mumbai, IN (2013 - 2014)
- Maharashtra, IN (2014)
Company Filing History:
Years Active: 2011-2014
Title: Innovations by Chandrakesan Muralidharan in Peptide Synthesis
Introduction
Chandrakesan Muralidharan is a notable inventor based in Mumbai, India, known for his significant contributions to the field of peptide synthesis. With a total of five patents to his name, Muralidharan has been instrumental in advancing the methodologies involved in the production of vital therapeutic peptides.
Latest Patents
His latest patents showcase innovative processes that offer high yields and purified forms of peptides. One such patent is the "Process for the synthesis of 37-mer peptide pramlintide," which details an efficient production technique that enables the synthesis of the pramlintide peptide in a relatively pure form. The process also provides for further purification through preparative HPLC, ensuring high-quality output.
Another notable patent is the "Process for the synthesis of cyclic heptapeptide." This invention presents an improved method for the large-scale synthesis of cyclic heptapeptides using Fmoc solid-phase synthesis techniques. This process involves assembling the peptide on solid support resin with a careful approach that utilizes C1-C4 alcohols as substitutes for organic nitriles, significantly enhancing safety, reducing costs, and promoting an eco-friendly manufacturing environment.
Career Highlights
Chandrakesan Muralidharan currently contributes his expertise at USV Private Limited, where he plays a key role in peptide synthesis research. His dedication to innovation is evident in the patents he has developed, which not only push the boundaries of peptide production but also align with contemporary needs for safer, more efficient methodologies.
Collaborations
Muralidharan collaborates with talented individuals like Nikhil Umesh Mohe and Divya Lal Saksena, fostering a collaborative environment that encourages creative problem-solving and innovation in their field. These partnerships enhance their collective ability to pursue advanced research and development in peptide synthesis.
Conclusion
Chandrakesan Muralidharan’s work in peptide synthesis represents a crucial advancement in the pharmaceutical industry. His innovative approaches not only improve the efficiency and safety of peptide production but also contribute significantly to the therapeutic options available for various medical conditions. As he continues to develop new methods and collaborate with fellow inventors, Muralidharan's impact on the field is likely to grow even further.