The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Jan. 17, 2011
Divya Lal Saksena, Mumbai, IN;
Chandrakesan Muralidharan, Mumbai, IN;
Lester Lobo, Mumbai, IN;
Digamber Shripati Pawar, Mumbai, IN;
Nikhil Umesh Mohe, Mumbai, IN;
Radhakishnan Venkatasubramanian Tarur, Mumbai, IN;
Divya Lal Saksena, Mumbai, IN;
Chandrakesan Muralidharan, Mumbai, IN;
Lester Lobo, Mumbai, IN;
Digamber Shripati Pawar, Mumbai, IN;
Nikhil Umesh Mohe, Mumbai, IN;
Radhakishnan Venkatasubramanian Tarur, Mumbai, IN;
USV, Ltd., Mumbai, IN;
Abstract
The present invention relates to an improved process for the large scale synthesis of cyclic heptapeptide using Fmoc solid phase synthesis technique. The described process assembles the peptide on a solid support resin by coupling to one another by peptide bonds to obtain a peptide wherein the coupling of cysteine to the resin employs a combination of solvents to reduce cysteine racemization. The process described relates to the use of C1-C4 alcohols as total substitute to organic nitriles thus making the process cost effective, non-toxic and eco-friendly.