Location History:
- Mumbai, IN (2011 - 2014)
- Maharashtra, IN (2014)
Company Filing History:
Years Active: 2011-2014
Title: Innovations by Nikhil Umesh Mohe: A Journey of Synthesizing Breakthrough Peptides
Introduction
Nikhil Umesh Mohe, based in Mumbai, India, is a notable inventor with a remarkable portfolio of five patents. His expertise lies in the field of peptide synthesis, contributing to significant advancements in pharmaceutical applications. With a focus on creating effective and environmentally friendly processes, Nikhil's work has made a notable impact in the industry.
Latest Patents
Among his latest inventions is a groundbreaking process for the synthesis of the 37-mer peptide pramlintide. This innovative process offers a high-yield synthesis of the peptide in a relatively pure form, with further purification achievable through preparative HPLC. Another significant patent is an improved process for the large-scale synthesis of cyclic heptapeptide using Fmoc solid-phase synthesis technique. This method allows for the assembly of peptides on a solid support resin, employing a combination of solvents to minimize cysteine racemization. Remarkably, his process replaces organic nitriles with C1-C4 alcohols, making it cost-effective, non-toxic, and eco-friendly.
Career Highlights
Nikhil Umesh Mohe's career is marked by his role in Usv Private Limited, where he has leveraged his knowledge to drive innovations in peptide synthesis. His dedication to research and development has enabled the company to enhance its capabilities in producing vital compounds for therapeutic applications.
Collaborations
Nikhil has worked alongside esteemed colleagues, including Divya Lal Saksena and Chandrakesan Muralidharan. Their collaboration has fostered a dynamic environment for creative problem-solving and the development of novel solutions in the field of peptide synthesis.
Conclusion
Nikhil Umesh Mohe’s contributions through his patents illustrate a commitment to advancing science and technology. His innovative approaches not only enhance the synthesis of critical peptides but also emphasize sustainable practices in the pharmaceutical industry. As he continues to push the boundaries of innovation, Nikhil stands as a key figure in the realm of peptide research and development.