The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8586710 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 19, 2013

Filed:

May. 04, 2009
Applicants:

Nikhil Umesh Mohe, Mumbai, IN;

Dinesh Kumar Paliwal, Mumbai, IN;

Divya Lal Saksena, Mumbai, IN;

Chandrakesan Muralidharan, Mumbai, IN;

Rakesh Shekhawat, Mumbai, IN;

Sagar Satyanarayan Zawar, Mumbai, IN;

Inventors:

Nikhil Umesh Mohe, Mumbai, IN;

Dinesh Kumar Paliwal, Mumbai, IN;

Divya Lal Saksena, Mumbai, IN;

Chandrakesan Muralidharan, Mumbai, IN;

Rakesh Shekhawat, Mumbai, IN;

Sagar Satyanarayan Zawar, Mumbai, IN;

Assignee:

USV, Ltd., Mumbai, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/02 (2006.01); C07K 1/107 (2006.01); C07K 14/535 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for improving pegylation reaction yield of r-metHuG-CSF comprising conjugating r-metHuG-CSF to a PEG aldehyde at a free amine moiety at the N terminal end on the G-CSF in presence of a reducing agent in a pegylation buffer solution comprising a polyol having the formula CHOwhere n is from 3 to 6, or a carbohydrate, or a derivative thereof wherein the concentration of said polyol or carbohydrate or derivative thereof is in the range of 0.1% to 10% w/w.


Find Patent Forward Citations

Mohe, Nikhil. (2013). Process for gram scale production of peg-r-methug-csf (U.S. Patent No. 8586710). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8586710

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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