Dinesh Kumar Paliwal

Title: Dinesh Kumar Paliwal: Innovator in PEGylation Technology

Introduction

Dinesh Kumar Paliwal is a notable inventor based in Mumbai, India. He has made significant contributions to the field of biochemistry, particularly in the area of PEGylation. His work focuses on enhancing the efficiency of drug formulations, which can lead to improved therapeutic outcomes.

Latest Patents

Dinesh Kumar Paliwal holds a patent for a process titled "Process for gram scale production of PEG-r-metHuG-CSF." This invention relates to a method for improving the pegylation reaction yield of r-metHuG-CSF. The process involves conjugating r-metHuG-CSF to a PEG aldehyde at a free amine moiety at the N-terminal end on the G-CSF. This is done in the presence of a reducing agent within a pegylation buffer solution that includes a polyol or carbohydrate derivative. The concentration of these components ranges from 0.1% to 10% w/w, which is crucial for optimizing the reaction yield.

Career Highlights

Dinesh Kumar Paliwal is currently associated with USV Private Limited, where he applies his expertise in drug development and formulation. His innovative approach has contributed to advancements in the pharmaceutical industry, particularly in the production of biopharmaceuticals.

Collaborations

Dinesh has collaborated with several professionals in his field, including Rakesh Shekhawat and Divya Lal Saksena. These collaborations have fostered a productive environment for research and development, leading to significant advancements in their respective projects.

Conclusion

Dinesh Kumar Paliwal is a prominent figure in the field of PEGylation technology, with a focus on improving drug formulation processes. His contributions through patents and collaborations highlight his commitment to innovation in the pharmaceutical industry.