Schwenksville, PA, United States of America

Chandra Vargeese

USPTO Granted Patents = 54 

 

 

Average Co-Inventor Count = 4.4

ph-index = 21

Forward Citations = 1,362(Granted Patents)

Forward Citations (Not Self Cited) = 1,192(Oct 12, 2025)


Inventors with similar research interests:


Location History:

  • Thornton, CO (US) (2000 - 2007)
  • Blue Bell, PA (US) (2010)
  • Broomfield, CO (US) (2009 - 2014)
  • Cambridge, MA (US) (2016 - 2020)
  • Schwenksville, PA (US) (2008 - 2023)

Company Filing History:


Years Active: 2000-2025

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54 patents (USPTO):

Title: Chandra Vargeese: A Trailblazer in Innovation and Invention

Introduction:

Throughout his remarkable career, Chandra Vargeese has made significant contributions to various industries, including technology, healthcare, and consumer electronics. With a sharp and innovative mindset, Vargeese's problem-solving abilities have led to groundbreaking inventions that have garnered widespread recognition. This article delves into his latest patents, career highlights, collaborations, and the impact of his work in the field of innovation.

Latest Patents:

Chandra Vargeese's expertise has resulted in the creation of 50 patents, showcasing his commitment to pushing boundaries and solving complex problems. Among his recent patents are two notable inventions:

1. Oligonucleotide compositions and methods thereof:

This patent encompasses the synthesis of oligonucleotides, with a focus on understanding the impact of their structural elements, including base sequence, chemical modifications, conjugation with additional chemical moieties, and stereochemistry. By investigating these factors, Vargeese aims to optimize the properties and activities of oligonucleotides, such as knockdown ability, stability, and delivery. The patent also highlights the potential therapeutic applications in the treatment of C9orf72-related disorders.

2. Compounds, compositions, and methods for synthesis:

This patent focuses on technologies for stereoselective synthesis, providing reagents and methods for the construction of challenging internucleotidic linkages. By developing chirally controlled preparation processes, Vargeese aims to enhance yields and achieve high levels of stereoselectivity. The patent also discusses the use of compounds as chiral auxiliaries and reagents for oligonucleotide synthesis.

Career Highlights:

Chandra Vargeese's illustrious career has seen him contribute to leading companies in the field of innovation. He has made significant professional achievements during his tenure at Sirna Therapeutics, Inc., and Wave Life Sciences Ltd, both renowned organizations in the healthcare and biotechnology sectors. His groundbreaking inventions and research have left lasting impacts on these companies and the broader scientific community.

Collaborations:

Throughout his career, Vargeese has collaborated with distinguished professionals in his field. Notable collaborations include working with esteemed colleagues such as Weimin Wang and James A McSwiggen. By joining forces with like-minded individuals, Vargeese has been able to pool expertise, exchange ideas, and further refine his innovative solutions.

Conclusion:

Chandra Vargeese's remarkable journey through innovation and invention is an inspiration to aspiring inventors in diverse industries. With an exemplary record of patents and groundbreaking contributions, Vargeese has proven himself as a pioneer in the field of oligonucleotide synthesis and stereoselective synthesis. His work not only presents novel solutions but also holds great promise for the treatment of various disorders. As Chandra Vargeese continues to push the boundaries of innovation, his contributions will undoubtedly shape the future of scientific advancements.

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